Channel opener

A channel opener, also known as a channel activator, is a type of drug which facilitates ion flow through ion channels.

They include the following:

  • Potassium channel openers
  • Calcium channel openers
  • Sodium channel openers
  • Chloride channel openers
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See also

  • Channel blocker
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Pharmacomodulation
Types
  • ♦ Enzyme: Inducer
  • Inhibitor
  • ♦ Ion channel: Opener
  • Blocker
  • ♦ Receptor: Agonist
  • Partial agonist
  • Antagonist
  • Inverse agonist
  • Positive allosteric modulator (PAM)
  • Negative allosteric modulator (NAM)
  • ♦ Miscellaneous: Precursor
  • Cofactor
Classes
Enzyme
see Enzyme inhibition
Ion channel
See Ion channel modulators
Receptor &
transporter
BA/M
Adrenergic
Dopaminergic
Histaminergic
Serotonergic
AA
GABAergic
Glutamatergic
Cholinergic
Cannabinoidergic
Opioidergic
Other
Miscellaneous
  • Cofactor (see Enzyme cofactors)
  • Precursor (see Amino acids)
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Calcium
VDCCsTooltip Voltage-dependent calcium channels
Blockers
Activators
Potassium
VGKCsTooltip Voltage-gated potassium channels
Blockers
Activators
IRKsTooltip Inwardly rectifying potassium channel
Blockers
Activators
  • GIRKTooltip G protein-coupled inwardly rectifying potassium channel-specific: ML-297 (VU0456810)
KCaTooltip Calcium-activated potassium channel
Blockers
  • BKCa-specific: Ethanol (alcohol)
  • GAL-021
Activators
K2PsTooltip Tandem pore domain potassium channel
Blockers
Activators
Sodium
VGSCsTooltip Voltage-gated sodium channels
Blockers
Activators
ENaCTooltip Epithelial sodium channel
Blockers
Activators
  • Solnatide
ASICsTooltip Acid-sensing ion channel
Blockers
Chloride
CaCCsTooltip Calcium-activated chloride channel
Blockers
Activators
CFTRTooltip Cystic fibrosis transmembrane conductance regulator
Blockers
Activators
Unsorted
Blockers
Others
TRPsTooltip Transient receptor potential channels
  • See here instead.
LGICsTooltip Ligand gated ion channels
  • See here instead.
See also: Receptor/signaling modulators • Transient receptor potential channel modulators


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