| 蛋白酪氨酸磷酸酶C型受體 |
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| 已知的結構 |
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| PDB | 直系同源搜索: PDBe RCSB |
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| PDBID列表 |
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1YGU、1YGR、5FMV、5FN6、5FN7 |
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| 識別號 |
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| 别名 | PTPRC；, B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase receptor type C |
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| 外部ID | OMIM：151460 MGI：97810 HomoloGene：2126 GeneCards：PTPRC |
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| 相關疾病 |
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| 溃疡性结肠炎[1] |
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| RNA表达模式 |
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| 查阅更多表达数据 |
| 基因本體 |
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| 分子功能 | • phosphoprotein phosphatase activity
• phosphatase activity
• 血浆蛋白结合
• transmembrane receptor protein tyrosine phosphatase activity
• protein kinase binding
• 水解酶活性
• protein tyrosine phosphatase activity
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| 細胞組分 | • integral component of membrane
• 膜
• 粘着斑
• 细胞膜
• integral component of plasma membrane
• cell surface
• 脂筏模型
• 外排體
• external side of plasma membrane
• secretory granule membrane
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| 生物學過程 | • B cell receptor signaling pathway
• cell cycle phase transition
• release of sequestered calcium ion into cytosol
• negative regulation of protein kinase activity
• bone marrow development
• stem cell development
• 蛋白质去磷酸化
• negative regulation of cytokine-mediated signaling pathway
• positive regulation of hematopoietic stem cell migration
• regulation of cell cycle
• negative regulation of cell adhesion involved in substrate-bound cell migration
• negative regulation of T cell mediated cytotoxicity
• cell surface receptor signaling pathway
• B cell proliferation
• T cell differentiation
• positive regulation of B cell proliferation
• defense response to virus
• positive regulation of T cell proliferation
• hematopoietic progenitor cell differentiation
• positive regulation of antigen receptor-mediated signaling pathway
• T cell receptor signaling pathway
• positive regulation of stem cell proliferation
• 去磷酸化
• positive regulation of protein kinase activity
• peptidyl-tyrosine dephosphorylation
• neutrophil degranulation
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| Sources:Amigo / QuickGO |
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| 直系同源 |
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| 物種 | 人類 | 小鼠 |
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| Entrez | | |
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| Ensembl | |
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ENSG00000081237
ENSG00000262418 |
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| UniProt | | |
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| mRNA序列 | |
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NM_001267798
NM_002838
NM_080921
NM_080922 |
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NM_001111316
NM_001268286
NM_011210 |
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| 蛋白序列 | |
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NP_001254727
NP_002829
NP_563578
NP_563578.2
NP_002829.3 |
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NP_001104786
NP_001255215
NP_035340 |
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| 基因位置（UCSC） | Chr 1: 198.64 – 198.76 Mb | Chr 1: 137.99 – 138.1 Mb |
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| PubMed查找 | [4] | [5] |
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| 維基數據 |
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. PMID 2169617. doi:10.1073/pnas.87.18.7000. （原始内容存档于2019-10-17）. 
