Deserpidine
Antihypertensive drug
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IUPAC name Methyl 17α-methoxy-18β-[(3,4,5-trimethoxybenzoyl)oxy]-3β,20α-yohimban-16β-carboxylate | |
Systematic IUPAC name Methyl (1S,2R,4R,4aS,13bR,14aS)-2-methoxy-3-[(3,4,5-trimethoxybenzoyl)oxy]-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2′,3′:3,4]pyrido[1,2-b]isoquinoline-1-carboxylate | |
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ECHA InfoCard | 100.004.551 |
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Properties | |
Chemical formula | C32H38N2O8 |
Molar mass | 578.662 g·mol−1 |
Pharmacology | |
C02AA05 (WHO) | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references |
Chemical compound
Deserpidine (INN) or reserpidine (USAN) is an antihypertensive drug structurally related to reserpine[1] which occurs naturally in Rauvolfia spp.
References
- ^ Fulton, S. C.; Healy, M. D. (1976). "Comparison of the effectiveness of deserpidine, reserpine, and alpha-methyltyrosine on brain biogenic amines". Federation Proceedings. 35 (14): 2558–2562. PMID 11134.
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(antagonize α-adrenergic
vasoconstriction)
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Peripheral |
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Serotonin receptor antagonists | |
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Endothelin receptor antagonists (for PHTooltip Pulmonary hypertension) |
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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