Beta-galaktozidaza
| Beta-galaktozidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 | |||||||||
| Identifikatori | |||||||||
| EC broj | 3.2.1.23 | ||||||||
| CAS broj | 2604851 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Beta-galaktozidaza (EC 3.2.1.23, beta-laktozidaza, maksilakt, hidrolakt, beta-D-laktozidaza, S 2107, laktozim, trilaktaza, beta-D-galaktanaza, orizatim, sumiklat) je enzim sa sistematskim imenom beta-D-galaktozid galaktohidrolaza.[1][2][3][4][5][6][7][8] Ovaj enzim katalizuje sledeću hemijsku reakciju
- hidroliza terminalnih, neredukujućih beta-D-galaktoznih ostataks beta-D-galaktozidi
Pojedini enzimi iz ove grupe hidrolizuju alfa-L-arabinozide.
Reference
- ↑ Blakely, J.A. and MacKenzie, S.L. (1969). „Purification and properties of a β-hexosidase from Sporobolomyces singularis”. Can. J. Biochem. 47: 1021-1025. PMID 5389663.
- ↑ Kuby, S.A. and Lardy, H.A. (1953). „Purification and kinetics of β-D-galactosidase from Escherichia coli, strain K-12”. J. Am. Chem. Soc. 75: 890-896.
- ↑ Kuo, C.H. and Wells, W.W. (1978). „β-Galactosidase from rat mammary gland. Its purification, properties, and role in the biosynthesis of 6β-O-D-galactopyranosyl myo-inositol”. J. Biol. Chem. 253: 3550-3556. PMID 418065.
- ↑ Landman, O.E. (1957). „Properties and induction of β-galactosidase in Bacillus megaterium”. Biochim. Biophys. Acta 23: 558-569. PMID 13426167.
- ↑ Llanillo, M., Perez, N. and Cabezas, J.A. (1977). „β-Galactosidase and β-glucosidase activities of the same enzyme from rabbit liver”. Int. J. Biochem. 8: 557-564.
- ↑ Monod, J. and Cohn, M. (1952). „La biosynthèse induite des enzymes (adaptation enzymatique)”. Adv. Enzymol. Relat. Subj. Biochem. 13: 67-119. PMID 14943665.
- ↑ Wallenfels, K. and Malhotra, O.P. (1960). Boyer, P.D., Lardy, H. and Myrbäck, K.. ur. The Enzymes. 4 (2nd izd.). New York: Academic Press. str. 409-430.
- ↑ Asp, N.G., Dahlqvist, A. and Koldovský, O. (1969). „Human small-intestinal β-galactosidases. Separation and characterization of one lactase and one hetero β-galactosidase”. Biochem. J. 114: 351-359. PMID 5822067.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
- Wallenfels, K. and Malhotra, O.P. (1960). Boyer, P.D., Lardy, H. and Myrbäck, K.. ur. The Enzymes. 4 (2nd izd.). New York: Academic Press. str. 409-430.
Vanjske veze
- MeSH Beta-galactosidase
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
