OR7G1

Protein-coding gene in the species Homo sapiens
OR7G1
Identifiers
AliasesOR7G1, OR19-15, OR19-8, OR7G1P, olfactory receptor family 7 subfamily G member 1
External IDsMGI: 3030688; HomoloGene: 128144; GeneCards: OR7G1; OMA:OR7G1 - orthologs
Gene location (Human)
Chromosome 19 (human)
Chr.Chromosome 19 (human)[1]
Chromosome 19 (human)
Genomic location for OR7G1
Genomic location for OR7G1
Band19p13.2Start9,114,828 bp[1]
End9,115,763 bp[1]
Gene location (Mouse)
Chromosome 9 (mouse)
Chr.Chromosome 9 (mouse)[2]
Chromosome 9 (mouse)
Genomic location for OR7G1
Genomic location for OR7G1
Band9|9 A2Start19,477,731 bp[2]
End19,478,678 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • blood

  • multicellular organism
    n/a
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • G protein-coupled receptor activity
  • signal transducer activity
  • olfactory receptor activity
Cellular component
  • plasma membrane
  • membrane
  • integral component of membrane
Biological process
  • sensory perception of smell
  • detection of chemical stimulus involved in sensory perception of smell
  • signal transduction
  • response to stimulus
  • G protein-coupled receptor signaling pathway
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

125962

258515

Ensembl

ENSG00000161807

ENSMUSG00000095667

UniProt

Q8NGA0

n/a

RefSeq (mRNA)

NM_001005192

NM_146522

RefSeq (protein)

NP_001005192

n/a

Location (UCSC)Chr 19: 9.11 – 9.12 MbChr 9: 19.48 – 19.48 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 7G1 is a protein that in humans is encoded by the OR7G1 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000161807 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000095667 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: OR7G1 olfactory receptor, family 7, subfamily G, member 1".

Further reading

  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX 10.1.1.135.3652. doi:10.1006/geno.2002.6830. PMID 12213199.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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Class I
(fish-like receptors)
Family 51
Family 52
Family 56
Class II
(tetrapod specific receptors)
Family 1
Family 2
Family 3
Family 4
Family 5
Family 6
Family 7
Family 8
Family 9
Family 10
Family 11
Family 12
Family 13


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