Dennie–Marfan syndrome
Medical condition
| Dennie–Marfan syndrome | |
|---|---|
| Specialty | Neurology |
Dennie–Marfan syndrome is a syndrome in which there is association of spastic paraplegia of the lower limbs and mental retardation in children with congenital syphilis.[1] Both sexes are affected, and the onset of the disease can be acute or insidious, with slow progression from weakness to quadriplegia. Epilepsy, cataract, and nystagmus may also be found.[citation needed]
The syndrome was described by Charles Clayton Dennie in 1929,[2] and Antoine Marfan in 1936.[3]
References
- ^ M.D, Mark E. Williams (2009). Geriatric Physical Diagnosis: A Guide to Observation and Assessment. McFarland. p. 56. ISBN 9780786451609.
- ^ Dennie CC. Partial paralysis of the lower extremities in children, accompanied by backward mental development. Am J Syphilis 1929; 13: 157–163
- ^ Marfan AB. Paraplégie spasmodique avec troubles cérébraux d’origine hérédo-syphilitique chez les grands enfants. Revue Franc Pédiat 1936; 12: 1–16
External links
- Dennie-Marfan syndrome at Who Named It?
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Signs and symptoms relating to infectious diseases
- syphilis
- Hutchinson's teeth
- Hutchinson's triad
- Westphal's sign
- Clutton's joints
- Dennie–Marfan syndrome
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