ATP6AP1 |
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Identifiers |
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Aliases | ATP6AP1, 16A, ATP6IP1, ATP6S1, Ac45, CF2, VATPS1, XAP-3, XAP3, ATPase H+ transporting accessory protein 1 |
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External IDs | OMIM: 300197; MGI: 109629; HomoloGene: 914; GeneCards: ATP6AP1; OMA:ATP6AP1 - orthologs |
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Gene location (Human) |
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| Chr. | X chromosome (human)[1] |
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| Band | Xq28 | Start | 154,428,633 bp[1] |
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End | 154,436,516 bp[1] |
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Gene location (Mouse) |
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| Chr. | X chromosome (mouse)[2] |
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| Band | X A7.3|X 37.96 cM | Start | 73,340,703 bp[2] |
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End | 73,348,327 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - Brodmann area 10
- paraflocculus of cerebellum
- islet of Langerhans
- stromal cell of endometrium
- right hemisphere of cerebellum
- right frontal lobe
- anterior pituitary
- frontal pole
- middle frontal gyrus
- cingulate gyrus
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| Top expressed in | - stroma of bone marrow
- dentate gyrus of hippocampal formation granule cell
- superior frontal gyrus
- primary visual cortex
- calvaria
- granulocyte
- epithelium of stomach
- cerebellar cortex
- anterior horn of spinal cord
- hippocampus proper
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - nucleotide binding
- proton-transporting ATP synthase activity, rotational mechanism
- transporter activity
- proton-transporting ATPase activity, rotational mechanism
- ATP binding
| Cellular component | - integral component of membrane
- proton-transporting V-type ATPase, V1 domain
- membrane
- proton-transporting two-sector ATPase complex
- endosome membrane
- extracellular exosome
- endoplasmic reticulum
- endoplasmic reticulum membrane
- endoplasmic reticulum-Golgi intermediate compartment membrane
- plasma membrane proton-transporting V-type ATPase complex
| Biological process | - insulin receptor signaling pathway
- transferrin transport
- pH reduction
- ion transport
- positive regulation of bone resorption
- positive regulation of osteoclast development
- establishment of organelle localization
- ion transmembrane transport
- positive regulation of osteoblast differentiation
- positive regulation of ERK1 and ERK2 cascade
- positive regulation of exocytosis
- cellular iron ion homeostasis
- cellular response to increased oxygen levels
- transport
- regulation of cellular pH
- proton transmembrane transport
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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NM_018794 NM_001358375 NM_001358380 |
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RefSeq (protein) | | |
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NP_061264 NP_001345304 NP_001345309 |
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Location (UCSC) | Chr X: 154.43 – 154.44 Mb | Chr X: 73.34 – 73.35 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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